Endocrine Abstracts

Introduction: Premature ovarian insufficiency (POI) affects approximately 1% of females. In POI, hormone replacement manages symptoms and reduces the risk of bone mineral density (BMD) loss as oestrogen acts to enhance bone deposition in bone remodelling. Oestrogen may be given either as synthetic oestrogen (ethinylestradiol) as in most combined oral contraceptives (COCP), or as physiological oestrogen (oestradiol) as in hormone replacement therapy (HRT preparations) and a sel...

Objectives: A retrospective review of adult patients with Turner syndrome (TS) attending a joint Turner syndrome clinic.Methods: Sixty-two adult patients with TS clinic were identified. Data was collected from case notes and electronic records.Results: Diagnosis was prenatal/at birth in 20%, 1–10 years in 29%, 11–20 years in 47% and after 21 years in one patient. Common presenting complaints were short stature (51%) and p...